Scientists discover new and simple way to stop the spread of melanoma
Australian scientists have made a breakthrough discovery that could increase skin cancer survival rates. Experts from the University of Queensland have uncovered a new and simple method to stop the spread of melanoma, which could have an 'enormous impact' on cancer patients.
By identifying how and when the tumours are formed, scientists have discovered a way to 'switch the cells off' and therefore stop the cancer developing.
Speaking of the new method, Kiarash Khosrotehrani of University of Queensland's Diamantina Institute said: 'It's actually fairly simple.
For tumours to spread, they have to have a blood supply and those blood vessels are the way tumours extend to the other parts of the body.
'Those blood vessels are formed initially by an influx of stem cells and that is the crunch of our study,' he added.
Melanoma, which occurs when the pigment-producing cells that give colour to the skin become cancerous, can be stopped by pinpointing the stem cells that form the blood vessels in a 'new approach that could make [all] the difference'.
'A drug already on the market has been used to slow down the stem cells and effectively stop the whole process of metastasis,' Dr Khosrotehrani said.
'Our research has the potential of offering something to patients, that once we cut a tumour out we can give them something to stop the formation of these blood vessels and the spread of a tumour.
'If we can do that, we can probably improve their survival rate in the long term,' Dr Khosrotehrani added.
Researcher Jatin Patel said melanoma's ability to quickly spread from the skin to other parts of the body was what made it so deadly.
'We know that before tumours spread to places like lymph nodes or lungs, the body starts growing extra blood vessels in these areas - almost as if preparing special 'niches' for the cancer.
'If the body doesn't prepare them, then the cancer won't grow there,' she said. Their next study will focus on blocking the development of these niches.
A clinical trial will be held to test the ability of the drug to stop these stem cells forming blood vessels. In Australia, there are 14,000 new diagnoses of melanoma each year - and almost 2000 deaths from the skin cancer.
The nation has the second highest rate of melanoma in the world. Australian scientists have made a breakthrough discovery that could increase skin cancer survival rates.
Experts from the University of Queensland have uncovered a new and simple method to stop the spread of melanoma, which could have an 'enormous impact' on cancer patients.
By identifying how and when the tumours are formed, scientists have discovered a way to 'switch the cells off' and therefore stop the cancer developing.
Speaking of the new method, Kiarash Khosrotehrani of University of Queensland's Diamantina Institute said: 'It's actually fairly simple.
For tumours to spread, they have to have a blood supply and those blood vessels are the way tumours extend to the other parts of the body.
'Those blood vessels are formed initially by an influx of stem cells and that is the crunch of our study,' he added.
Melanoma, which occurs when the pigment-producing cells that give colour to the skin become cancerous, can be stopped by pinpointing the stem cells that form the blood vessels in a 'new approach that could make [all] the difference'.
'A drug already on the market has been used to slow down the stem cells and effectively stop the whole process of metastasis,' Dr Khosrotehrani said.
'Our research has the potential of offering something to patients, that once we cut a tumour out we can give them something to stop the formation of these blood vessels and the spread of a tumour.
'If we can do that, we can probably improve their survival rate in the long term,' Dr Khosrotehrani added.
Researcher Jatin Patel said melanoma's ability to quickly spread from the skin to other parts of the body was what made it so deadly.
'We know that before tumours spread to places like lymph nodes or lungs, the body starts growing extra blood vessels in these areas - almost as if preparing special 'niches' for the cancer.
'If the body doesn't prepare them, then the cancer won't grow there,' she said. Their next study will focus on blocking the development of these niches.
A clinical trial will be held to test the ability of the drug to stop these stem cells forming blood vessels. In Australia, there are 14,000 new diagnoses of melanoma each year - and almost 2000 deaths from the skin cancer.
The nation has the second highest rate of melanoma in the world. Australian scientists have made a breakthrough discovery that could increase skin cancer survival rates.
Experts from the University of Queensland have uncovered a new and simple method to stop the spread of melanoma, which could have an 'enormous impact' on cancer patients.
By identifying how and when the tumours are formed, scientists have discovered a way to 'switch the cells off' and therefore stop the cancer developing.
Speaking of the new method, Kiarash Khosrotehrani of University of Queensland's Diamantina Institute said: 'It's actually fairly simple.
For tumours to spread, they have to have a blood supply and those blood vessels are the way tumours extend to the other parts of the body.
'Those blood vessels are formed initially by an influx of stem cells and that is the crunch of our study,' he added.
Melanoma, which occurs when the pigment-producing cells that give colour to the skin become cancerous, can be stopped by pinpointing the stem cells that form the blood vessels in a 'new approach that could make [all] the difference'.
'A drug already on the market has been used to slow down the stem cells and effectively stop the whole process of metastasis,' Dr Khosrotehrani said.
'Our research has the potential of offering something to patients, that once we cut a tumour out we can give them something to stop the formation of these blood vessels and the spread of a tumour.
'If we can do that, we can probably improve their survival rate in the long term,' Dr Khosrotehrani added.
Researcher Jatin Patel said melanoma's ability to quickly spread from the skin to other parts of the body was what made it so deadly.
'We know that before tumours spread to places like lymph nodes or lungs, the body starts growing extra blood vessels in these areas - almost as if preparing special 'niches' for the cancer.
'If the body doesn't prepare them, then the cancer won't grow there,' she said. Their next study will focus on blocking the development of these niches.
A clinical trial will be held to test the ability of the drug to stop these stem cells forming blood vessels. In Australia, there are 14,000 new diagnoses of melanoma each year - and almost 2000 deaths from the skin cancer.
The nation has the second highest rate of melanoma in the world.
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