News on Youtube Aug 1 2018

There are two different ways on how to download Itch.io games for Windows PC.

I'll be showing you both methods that have their benefits and downsides.

Are you ready?

Now That's Gaming!

Let's head to Itch.io by typing it in the address bar and you'll be taken to the website

where you are able to try many free games, others you'll have to pay for.

Select a game you want to download by clicking on it.

This will take you to the creators' page where you will find a download button.

When clicking on the button, there are two things that can happen, one you will be able

to download the game to the folder of your choice or some creators may have an option

that pops up to name your price.

If you prefer not to pay just select "No, thanks just take me to the downloads."

You will be taken to another page where you can then download to your desired folder.

Once the download is complete, go to the folder, right-click on it and you should see "Extract

All".

This option is for Windows 7, 8.1, and Windows 10.

You can choose where you want the file to be extracted and to make it even easier, have

the "Show extracted files when complete" box checked.

This will automatically open that folder after it's done extracting.

Once that is complete, you should be able to open up the .EXE file and enjoy your game.

The second way to download and play these games is through the app from the Itch.io

website.

You'll need an account which is free and easy to sign-up with.

After that's done, click on "Download app" from the front website page which will

take you to a second page where you can choose which version is suited to you.

Currently, Windows, Mac OS, and Linux are supported.

Download the Itchsetup to a folder, find it and click on it to start up the short installation.

After that is done you can open up the app through the created itch desktop shortcut

and sign in with the same information you used to register on the website.

Now you're able to search for games like on the main website.

Installing these games, in my opinion, is easier, just go to a game you want to play

and on the right side, you can see the install button.

Select it and begin downloading the game, a tab will open up on the left side showing

the progress of your downloads.

Once it's finished, just launch the game by clicking here.

Two easy and simple ways to install games from Itch.io

If there are any questions you want to be answered or issues you run into, then post

them in the comments below.

And If you want to discover something new with the various Indie content I cover on

my channel, then consider subscribing.

Thank you for watching and have a fantastic day.

For more infomation >> How To Download Itch.io Games In 2018 | Two Simple Ways! - Duration: 3:09.

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For more infomation >> blouse back neck designs | simple maggam work blouse designs | Simple Life Hacks, Diy,TNBN Tv Live - Duration: 5:39.

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Simple Green Smoothies Our Mission: Fuel your Passion - Duration: 3:28.

When I started simple green smoothies it

Wasn't even a business idea. It was really just a solution for me and my family and friends to that

We were all struggling with exhaustion. And this was a natural way to get energy in your body that was super easy to do and

it worked so when the kids were really little I was

living off of grilled cheese sandwiches

Lucky Charms was my favorite cereal and I would eat that for dinner and I would drink tons of coffee because I'm so tired

I felt like my body was giving up on me

Like I'm 30 years old and I feel like I'm 60. It also didn't help that at that time

We were we were struggling like we were financially in a really hard place

That I had never experienced before and we also didn't have health insurance. So it was kind of like this

Chaotic moment where we didn't have a lot of things and so what we started doing was drinking a green smoothie

Every single day and this was a way that I could at least

focus on doing one thing right and I got to a point where I

would go halfway through the day and not be tired and I started thinking like

Okay

Like there's time in this day for me to figure out what I want now and what I want to do, and that was run

I wanted to get outside by myself.

No electronics and just breathe and sweat and push my body and that's what I started to do again.

By doing that I was getting stronger. I was getting more energy

But I also I started dreaming again and thinking about what did I want to do?

Who did I want to become I realized that I wanted to fly an airplane on my 32nd birthday

I went and took a discovery flight and flew an airplane.

Now I felt like I could do anything and it was because I was taking care of myself

All right, so life for us right now is pretty crazy waking up early getting them ready for school when the kids come home

It's like straight snack time homework. So we have a very full life and we love it all and I wouldn't trade it for anything.

One thing Ryan and I thought would be really cool was to turn our house into a little farm.

So it was a dream of ours to

wake up in the morning with our kids and have them be able to go outside and gather eggs from our chickens and

To have a duck that would swim in a little pond.

We also have done raised garden beds so that we could grow our own

kale and spinach and strawberries and tomatoes and so that's kind of what we've embraced as a family is

eating more plants and

feeling the best we can so that we can go after the things that we really care about

Once you drink a green smoothie

you don't want it to stop there like you want to keep feeling that greatness that energy and just

More of yourself than you ever felt before and to do that. You have to go further

And so now we're taking our community further who you are today

can be someone different tomorrow. If you just keep having that hope and taking steps forward no matter how small they are.

I would love for you to join me on this journey and see where it takes your life.

So head on over to our website simple green smoothies.com and get started today.

For more infomation >> Simple Green Smoothies Our Mission: Fuel your Passion - Duration: 3:28.

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Phases Of A Clinical Trial Made Simple - Duration: 7:37.

hey guys ECR G here back with another video today we're gonna be talking about

the phases of clinical trials hey guys ECR G here back with another video we've

got a really good one for you guys today this is a more clinical research

specific video so if you watch this channel and not really interested in

clinical research you can go ahead and just skip this video and watch one of

the other videos instead but today we're talking about the phases of clinical

trials now a lot of people may have heard about clinical trials they may

have learned about the phases of clinical trials in biology and thought

it might have been confusing or not but we're gonna go over it today nice and

easy for you to understand and for those of you who are trying to get into the

clinical research space this is helpful to know for your interviews that I'm

sure are coming up and so a lot of people think there are three phases of

clinical trials and that's a that's a good thought but they're actually more

than just three that you may know of so there's in addition to the phase 1 phase

2 phase 3 there's what's called a phase 4 which can happen after the drug is

already on the market and there's also a preclinical phase which is before phase

1 so all in all there are about five phases of clinical research

if you want to be complete there but of course the phase one two and three are

the main ones that's where most of the money and intensive energy expenditure

is is done and those are the three main ones so the first one we're going to

talk about is preclinical because we want to be complete here and the goal of

the preclinical phase is to test the to test an initial idea to see if it has

any effect so they may have a compound or something that they're thinking of

that they're working on and they just want to test it to see if it does

anything and so the preclinical phase is

different from all the rest because this is where they test it in animals so this

could be in rats mice any other animals that they may test it in so that's the

preclinical phase and this is before phase one and there they're just testing

the compound that they may have to see if it has any effect so that's the

preclinical then there's phase one and the goal of phase one is to find the

safest dosed to find the faith's safest dose and to find the most effective way

to deliver the drug and start thinking about the side effects so this is done

in a small cohort of healthy patients this does not have the the disease that

they're interested in looking at these are healthy patients and they just want

to find out about the side effects because though the smallest dose that

they find that has side effects will be the maximum dose used in the remainder

of the trial so that's interesting so that's that's phase one usually you know

just gonna have a few maybe ten or so healthy patients that do not have the

disease okay so then there is phase two of the clinical trial which was gonna

build on the results of Phase one like I said so the smallest dose that causes

side effects in Phase one will be the maximum dose used in Phase two and

there's gonna see how well the treatment works and there this is the this is the

first time that patients with the actual disease are introduced to the drug so

once again this is gonna be small probably probably bigger than phase one

in the terms of number of patients but it's gonna just be small just to see how

it is and if it's if the treatment is effective and it is safe then they're

gonna move on to Phase three and the key thing to know here is that this is the

first time the drug is introduced the drug or medical device or whatever it is

they're testing is introduced to patients with the affected disease

so if pal things go well in Phase two they're gonna move on to Phase three and

this is the largest group this is where the largest amount of money is spent

they can have hundreds sometimes thousands of patients and you know this

is where they do all the randomization and stuff like that I mean this is these

are huge a lot of money is spent on these phase three clinical trials and

the goal here is to really see if the new treatment is better than the current

standard of care so and and then this this is like the pretty much the final

part there's a phase four but this is most important and then they're gonna

submit the drug to the FDA if everything goes well in phase 3 phase 4 so I mean

obviously this is the huge part this could take years to you know run a phase

3 it's large-scale takes much longer than the phase 2 because you're dealing

with so many more patients you have to recruit all these patients etcetera etc

we're in phase 2 those are just healthy patients you know you could find those

anywhere so it's not gonna take as long to go through so that's that and then

there's a phase 4 which which the main goal is just to analyze how you know

it's being used on an everyday basis and the patients to see if it can remain on

the market so they take that data and they run a phase 4 study with it and

really understand if it's better or equal to the current standard of care

what the side effects are because sometimes you don't see the side effects

or all of the side effects and see how it's impacting people until it's already

on the market but they're continuing to study it and everyday you know people

and you know they're just making sure that everything is ok before they can

before it completes the face for completely

so that's all the phases right there so preclinical phase 1 phase 2 phase 3 and

then of course phase 4 and those are the phases of clinical trials guide not nice

nice and easy not as complicated as you might have thought I mentioned some of

the key distinctions between each of the phases so that's it in a nutshell guys

and if you like this video go ahead and like it if you want to see any more

clinical research related videos comment those down below you can email us at

elite clinical group at gmail.com and you know that's pretty much it for

today's video guys I already hit the red subscribe button take care

For more infomation >> Phases Of A Clinical Trial Made Simple - Duration: 7:37.

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Simple robots form a chain gang to solve complex problems - Duration: 3:13.

Researchers have shown that a swarm of reactive

robots can function as a team

to solve a complicated puzzle--

without reasoning or explicit programming.

They placed a swarm of 20 hockey-puck shaped robots

inside an arena

The swarm's goal was to enter each booth

in the correct order

The bots sport LED lights,

cameras, and infrared transceivers,

Only robots within close proximity--

within about 20 to 30 cm --

could communicate.

Each unit was programmed with the same

predefined roles:, guardian, runner, tail, or link.

At the start of each trial, all of the bots

are runners and move randomly about the field.

The first runners to enter each of the booths

become guardians, setting up just outside of the

booths to give instructions to other runners.

The guardians receives a signal from the booth.

If it is the first in the sequence the signal is yes.

If not, the guardian is in front of ether 2 or 3.

To navigate from booth to booth the robots form

a chain from the guardian of the first booth.

The last link in the chain is the tail

and searches in a sweeping motion for

a robot to become the next link in the chain.

Once the chain reaches the second guardian,

the process is repeated, creating a chain ending

at the remaining guardian.

The remaining free bots are runners and

use the chain as a pathway,

taking instruction from the guardians

whether or not to enter the booths.

A guardian that is unsure of whether it is in front

of booth 2 or 3 will ask a runner

that has performed exactly one task to enter its booths.

If this runner receives a yes signal from the booth,

the task is the second in the sequence.

Otherwise, it is the third.

Once the guardians have learned the position

of their task in the sequence, they will guide

the runners to complete the tasks

in the correct sequence.

Over 10 trials, the researchers showed that

the swarm was able to accomplish something

very complex through trial and error --

by only reacting to their nearby environment.

The study overturns conventional wisdom

that robots can solve complex tasks in only one

of two ways-- and not both.

1. They could either use deductive reasoning to plan

or 2. They could react in programmed ways

to set situations.

In this conglomeration of bots--both are happening.

The ability to plan emerges from

the interaction of simple reactive bots

And this type of swarm is scalable.

The same programming and sensors

could serve a swarm of 100 or 10,000.

While there's no immediate applications for this,

researchers working with these bots

are really seeking to expand our understanding

of how swarms of robots cooperate and become

more than the sum of their parts--like bees or ants.

At the end of the day, the old saying still rings true

there's no 'I' in team…

or in robot for that matter...

For more infomation >> Simple robots form a chain gang to solve complex problems - Duration: 3:13.

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The Simple EQ Trick For A Clean, Balanced Low End - BehindTheSpeakers.com - Duration: 7:17.

In this video, you'll discover a simple EQ trick that will help you craft a clear,

balanced low end in any mix.

Hey, this is Jason from Behind The Speakers, and if you're like most of my students you

probably struggle to get the low end in your mixes to sound right.

Maybe the kick and the bass are competing.

Maybe the low end sounds boomy or muddy.

Or maybe your mixes sound great in your studio, but when you take them out into the car the

low end totally falls apart.

If any of this sound familiar to you, you should know that you're not alone, because

mixing low end is just hard.

It's hard for everybody, whether you're an amateur or a pro.

And this trick that I'm going to show you today is going to make things easier for you.

It's going to help you approach the low end with more clarity and confidence.

Now one of the main challenges when it comes to mixing low end is that it can often be

difficult to hear what's going on in that area of the frequency spectrum.

Our ears are much more sensitive to midrange frequencies.

And so when it comes to mixing the low end, if you can't really hear what's going

on down there it makes it much more difficult to make good mixing decisions.

So this trick is almost like a magnifying glass.

It will help you zero in on that low end area.

And when you can do that, you can be much more discerning, and it just makes it easier

to make the right mixing decisions.

So I have a track here called "Best Man," by Dylan Owen.

And I'm going to show you how to apply this trick on this track, but let's take a listen

to the full mix first.

♪ Green as our grandparents trees, in our land of fantasy ♪

♪ There in pine bush, shoot through the acres with our lanterns leaking kerosene ♪

So you notice this is a hip hop track, and obviously in hip hop the low end is incredibly

important.

So the kick and the bass in this mix at this point I think are working really well together.

And one of the big parts of that was the fact that I got really good sounds to work with

as a mixer.

So the producer who produced this track did a really great job at choosing the rights

sounds - the kick and the bass - and they fit really well together.

And that's half the battle - just getting the right ingredients to start with will make

the mixing job so much easier.

But something else that I really tried to do in the mixing process was pay very close

attention to that low end and make sure that I was giving it the attention it deserved,

because in a hip hop track low end is everything.

So what I did was I added an EQ to the mix bus.

Now I added it at the end of all my other processing, and this is what I recommend you

do as well if you're using this trick.

So after any compression or other EQ, or limiting, just put it at the end of the line.

Now here I'm using the FabFilter Pro-Q 2, which is my favorite EQ.

You can really apply this technique with any EQ, you don't need this specific one.

This is just the one that I like.

So I have a bunch of presets that I've created for this EQ.

The one we're going to take a look at here is called subs only, and basically all this

is is a very simple low-pass filter.

And a low-pass filter cuts all the high end out and lets the lows pass, that's what

low-pass means.

So basically we have a filter here that's cutting everything above 170 Hz, so all we're

left with is the low end.

So I've found that number 170 Hz is a pretty good place to start cutting if you're using

this trick.

It's not essential that you use that specific number.

You can play around and find your own specific number that works best for you, specific frequency.

The other thing I just want to point out here is that the slope on the cut - so that's

how aggressive the cut is - is 18 dB per octave.

So a higher slope means that things drop off a lot more quickly.

So if we set this to - let's say 96, you can see it's like a straight line.

Whereas back at 18 dB, things are a little bit more gentle.

So I find that that number 18 dB for this technique works really well.

I would encourage you to play around and determine your own choice for that specific slope that

works best for you.

But the idea here is that now when we play back the mix through this filter, all we're

going to hear is the low end of the frequency spectrum in our mix.

And it's almost like, again, taking a magnifying glass up to that specific area of the frequency

spectrum.

So let's take a listen.

I'm going to turn the mix up a little bit so we can hear it more clearly.

So you can see and hear now we can actually just zero in on that low end information,

and we can start to discern what the relationship is between the kick and the bass in that low

end area.

Now the way that I use this technique is I don't spend a ton of time listening through

this filter.

I prefer listening to the whole mix, and it's important that you listen to all the frequencies

together primarily.

But when I'm really trying to zero in on maybe a specific high-pass filter or I'm

trying to work on the relationship between the kick and the bass, and I really want to

get a little bit more of a sense of what's going on in that area, that's when I'll

pull this up.

And I might flip it in for a minute or so and just listen to what's going on, and

I usually like to listen to the low end just on its own towards the end of the mix as well.

And not only do I do this with the low end, but I actually do this with the midrange and

the high end as well.

So you can see here I have a midrange-only preset that just cuts out the low end and

the high end and just zeros in on the midrange, and then I have a highs-only preset that just

allows me to listen to the high end.

The point here is that by using these filters - and specifically in the low end - I find

this is really the most useful.

Again, it just allows me to hear a little bit more of what's going on, and just zero

in for a second at what's happening down there, and just make better mixing decisions.

So play around with this technique.

Create a preset in your favorite EQ.

And I promise you, you know, especially if you're working on things like hip hop, being

able to zero in on that area and spending a couple minutes every mix just listening

to what's going on down there will help you make better low end mixing decisions,

and it's going to lead to a low end that sounds clearer and more balanced.

If you're ready to dive deeper, if you like this technique and you want to learn more,

I recommend that you download my free EQ cheatsheet, which is packed with more tips and tricks

that will add clarity and separation to your mixes just like the one that we talked about

today.

So if you want to download this, again it's completely free.

Just click the link in the video above or in the description below, and you'll download

this free cheatsheet right now.

Now before you go, leave a comment in the section below this video and let me know - what's

your go-to EQ plug-in?

I'd love to hear from you, so leave your answer in the comments section below.

I read every one and try to reply to as many as I can.

Thanks so much for watching, and you can check out more mixing tips right here on my YouTube

channel, or at BehindTheSpeakers.com.

For more infomation >> The Simple EQ Trick For A Clean, Balanced Low End - BehindTheSpeakers.com - Duration: 7:17.

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Experts: A 3D printed firearm isn't as simple as it sounds - Duration: 2:37.

For more infomation >> Experts: A 3D printed firearm isn't as simple as it sounds - Duration: 2:37.

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Simple Eats Cafe kicks-off Christmastime supply drive - Duration: 2:12.

For more infomation >> Simple Eats Cafe kicks-off Christmastime supply drive - Duration: 2:12.

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5 AWESOME SIMPLE LIFE HACKS & DIY - Duration: 4:51.

- Hello!

- If this were the technical drawing of our flying saucer,

it would look like this ...

- Doc, why are watermelons red inside?

- Well, it's because of the presence of lycopene...

- Do you remember, we had pink and purple, even blue watermelons on our planet...

- You are probably so blue, because you overate those blue watermelons in your childhood?

- Oh, c'mon!

I thought after applying this thing the sticker would dissolve itself.

- Yeah, together with the bowl ...