Thứ Ba, 28 tháng 11, 2017

News on Youtube Nov 28 2017

The C.I.A. Literally Controls EVERYTHING � Even Deep State

The C.I.A. is likewise controlled by much more secretive levels of command and control

State of the Nation

The following perceptive comment was sent by email to SOTN. It simply states the obvious

about the Central Intelligence Agency and its complete control of the United States

of America, and beyond.

It also shows just how extensive Deep State really is. Every publicly traded corporation,

for example, within the Anglo-American Axis is controlled, either directly or indirectly,

by the C.I.A. That�s why the U.S. Intelligence Community refers to it as The Company.

The Global Control Matrix (GCM) is actually the backbone of the New World Order, and functions

as a de facto One World Government. Deep State is just one critical piece of the GCM puzzle.

Just because the current World Shadow Government operates in total secrecy doesn�t mean it

doesn�t exist. The globalist New World Order has actually been here for well over a hundred

years.

The practical reality is that the World Shadow Government (WSG) rules over every square inch

of planet Earth � to varying degrees, of course. (Russia, for instance, has left the

reservation in many ways, but still has to play the game in many ways.)

The bottom line is that the C.I.A. is primarily the enforcement agency for the WSG. It was

recently written that the C.I.A. is the �enforcement agency for the Council on Foreign Relations�.

And that�s entirely true. However, the C.I.A. is also the enforcement agency for every other

entity within Deep State, both public and private, covert and overt.

Only with this correct understanding can the true magnitude of humanity�s problematic

predicament be comprehended. Essentially, a thoroughly rogue intelligence agency � the

largest in the world � has taken control of every sphere of life. In fact, the C.I.A.

acts with absolute impunity, whenever and wherever it so chooses to. As follows:

JFK Assassination Plot Was Coordinated and Conducted by the C.I.A.

And all the C.I.A. ever has to do to justify their never-ending criminal conspiracies is

claim that they are being implemented in the interest of �N A T I O N A L S E C U R I

T Y�. As if publicly executing a POTUS was carried out to make the nation more safe and

secure.

What a place!

State of the Nation November 26, 2017

N.B. What is remarkable is that the post below only represents the tip of the CIA-controlled

Deep State iceberg. It also illustrates why The U.S. Central Intelligence Agency Must

Be Shut Down before it shuts US down.

What Does the CIA Control?

Submitted by GA

The Mainstream Media is CIA (all TV, Radio, Newspapers & News Magazines).

Hollywood is CIA (all Motion Pictures and TV programs).

Google is CIA. Facebook is CIA.

Twitter is CIA. Microsoft is CIA.

Apple is CIA. IBM is CIA.

Intel is CIA. Hewlett Packard is CIA�..the list here is

endless, let�s just say all of Silicon Valley is CIA!

All Defense Contractors are CIA, like: Lockheed Martin is CIA.

General Dynamics is CIA. Northrup Grumman is CIA.

Raytheon is CIA. Boeing is CIA.

Halliburton is CIA. United Technologies is CIA.

Bechtel is CIA.

ISIS is CIA. Al Qaeda is CIA.

Al-Nusra is CIA The Bin Laden Family is CIA.

Saddam Hussein was CIA, who went rogue on the CIA. (There were no weapons of mass destruction,

as we know, Daddy Bush was pissed off at his rogue CIA Agent, Saddam, and THAT is why so

many U.S. soldiers had to die and get wounded in Iran.)

Noriega was CIA, who went rogue on the CIA. Castro was CIA, who went rogue on the CIA.

Soros is CIA & MI6.

Bush Family is CIA. Clinton Crime Family is CIA, especially the

Clinton Foundation. Obama Family is CIA.

The White House has been CIA for over 25 years.

The FBI is CIA. (obviously, or else the FBI would have shut down the Mafia years ago.

But they don�t do they? Because the CIA and the Mafia are joined at the hip. They

are partners in crime as the JFK assassination clearly demonstrated.

Monsanto is CIA.

The Las Vegas Massacre was CIA. Northern California UNnatural Fires were CIA.

9/11 was CIA/MI6/Mossad. Oklahoma City Bombing was CIA.

Aurora Movie Theater Massacre was CIA. Sandy Hook was CIA��this list too is endless.

Agenda 21 Depopulation Goals are CIA.

When I say CIA, I mean CIA/Deep State controlled.

Insiders call the CIA �The Company�. That makes sense now, doesn�t it?

6 Million people work for the CIA.

CIA/MI6 have their tentacles into EVERYTHING of value, GLOBALLY.

SERCO is CIA � and MI6 � and Mossad.

The CIA sets the AGENDA and Controls the Narrative.

Big Brother is CIA. They are everywhere: in your phone, on your PC, in your TV, in your

car, in your fridge, your smart meters, and in all surveillance cameras and spying devices

which are now everywhere. Even if these items are turned off, and you don�t pay the bill

and shut down services, they can still turn it on whenever they want to and listen and

watch you.

That was step one for total control. Next is step 2:

Agenda 21, Big Brother (CIA) wants you dead, either through deadly vaccines that injest

you with cancer and then cancer treatments that don�t work.

Agenda 21/Big Brother/Deep State/ CIA wants to decrease the global population through

disease, wars, pestilence, famine, weather modification (droughts and deluges, mudslides

and floods, earthquakes and volcanoes, massive hurricanes, ice storms, blizzards, tsunamis,

sink holes, you name it).

And, of course, through the promotion of rampant homosexuality (homos can�t reproduce).

Christian Western Civilization is being destroyed on purpose by importing Islam which never

assimilates and only brings division and civil wars. Just ask Gandhi. It got so bad in India,

they had to divide their land, and all Hindus and Christians staying in India, and the Muslims

went to Pakistan��.because militant Islam (Wahhabis) NEVER lives peacefully with anyone

else. So you have to ask, why is the CIA/Deep State flooding the USA with Muslims? To promote

Peace? No, to promote DIVISION and CONFLICT.

These are just some of the TRUTHS the CIA/Deep State does NOT want you to know about, and

that is why they HAVE TO CONTROL all media: TV, radio, newsprint, and now they are going

after the Internet with censorship.

You are supposed to remain in the dark, dumbed down, and swallow hook, line and sinker whatever

Big Brother CIA spoon feeds you from TV, radio, newsprint�.and the Internet. Everything

else if �fake news�, remember?

What has upset the status quo is a groundswell of truth getting out via the Internet and

Alternative Radio, YouTube and Instagram. A tipping point was reached last year, and

in spite of MASSIVE Vote Rigging on all levels, Trump still WON!. Trump is NOT CIA, thus the

nonstop smears from Mainstream Media!

For more infomation >> The C I A Literally Controls EVERYTHING … Even Deep State - Duration: 9:27.

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Russia warns North Korea and United States bound for 'APOCALYPSE' - DAILY NEWS - Duration: 3:16.

Russia warns North Korea and US bound for 'APOCALYPSE'

RUSSIA has warned the US and North Korea are heading for apocalypse in a chilling prediction

for the nuclear crisis.

Moscow diplomat Igor Morgulov warned the growing threat of confrontation could spiral into

a world-ending war.

He called on both sides and the other regional powers to have "common sense" and stand

down.

Russia has called for calm in the region after tensions reached new heights this year as

US President Donald Trump taunts Kim Jong-un.

North Korea has refused to bow to pressure from the US and UN to give up its quest for

nuclear missiles.

Russia shares a border with the rogue state on its eastern frontier, and Vladimir Putin

is believed to back Kim in war with the US.

Mr Morgulov said: "To my regret, I have to say that there is an apocalyptic scenario

for the development of events in this region.

"I hope that the regional community will have enough common sense to prevent this scenario

from becoming a reality."

He was speaking during a meeting in South Korea amid fears of an imminent missile test

by North Korea.

Putin's diplomat Morgulov – Russia's deputy foreign minister – called on the

South and the US to "exhale" and begin talks with the North.

Kim has not fired a missile for more than 70 days, but North Korea is now believed to

be carrying out winter war games.

He added: "If the restraint that Pyongyang has been demonstrating over the past two months

was met with proportionate response steps on the part of the United States and its allies,

it would be possible to start the second stage of our roadmap plan and start direct talks

between the United States and North Korea."

North Korea warned Russia it was ready to launch a nuclear strike on the US in a letter

addressed directly to Putin, it emerged earlier this year.

The rogue state is believed to be building up to firing a nuclear weapon out into the

Pacific – with a missile known as the Juche Bird.

An unannounced missile launch of this kind would be the ultimate provocation and could

spark World War 3.

Russia has urged both sides to stop walking towards war – calling on the US to move

its military might out of the region, and the North to comply with UN nuclear restrictions.

Kim is fighting a power struggle within North Korea at the moment, according to reports,

appointing his close allies to top jobs in the regime.

The US and North Korea have both threatened the other with total destruction amid fears

of war on the Korean Peninsula.

For more infomation >> Russia warns North Korea and United States bound for 'APOCALYPSE' - DAILY NEWS - Duration: 3:16.

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Regions of the United States Digital Story - Duration: 4:00.

The US can be categorized into four different geographic regions.

These four regions are the Northeast, the Southeast, the Great Plains, the Southwest,

and the Pacific Northwest.

Each region can be described by its climate and physical geography.

First, we are going to discuss the Northeast region of the United States.

This region includes Maine, Massachusetts, Rhode Island, Connecticut, New Hampshire,

Vermont, New York, Pennsylvania, New Jersey, Delaware, and Maryland.

The climate in this region is a humid, continental climate.

In the northernmost areas, the summers are cool.

In the winter, temperatures are frequently below freezing, and snow is common.

Physical geography in this region includes the Appalachian Mountains.

The region borders the Atlantic Ocean to the East and Canada to the North.

The population of this region is 63 million people.

Next, let's talk about the Southeast region of the United States.

This region includes West Virginia, Virginia, Kentucky, Tennessee, North Carolina, South

Carolina, Georgia, Alabama, Mississippi, Arkansas, Louisiana, and Florida.

The climate in this region is a humid subtropical climate.

The summers are hot.

Hurricanes and tropical storms can be common during the summer and fall months.

This region borders the Gulf of Mexico to the south.

A notable geographic feature is the Mississippi River.

Like the Northeast, this region also contains parts of the Appalachian Mountains, and borders

the Atlantic ocean to the East.

The population of this region is 82 million.

Moving Westward, we reach the Great Plains region of the United States.

This region includes Ohio, Indiana, Michigan, Illinois, Missouri, Wisconsin, Minnesota,

Iowa, Kansas, Nebraska, South Dakota, and North Dakota.

There is a humid continental climate in this region.

Snow is common in the winter, especially in the northern areas.

The Great Lakes are in this region, as well as the great plains.

The Mississippi River also flows through this part of the US.

The region borders Canada to the North.

The population of the Great Plains region is 67 million.

Next is the Southwest region.

This region includes Texas, Oklahoma, New Mexico, and Arizona.

This region has an interesting climate, with a semiarid steppe climate in the West and

a humid climate to the East.

Some areas could even be called alpine or desert.

Physical features of this region are the Rocky Mountains, the Colorado River, and the Grand

Canyon.

The region borders the Gulf of Mexico, and Mexico itself to the South.

The population of this region is 40 million.

Finally, we have reached the Pacific Northwest region of the United States.

This region includes Colorado, Wyoming, Montana, Idaho, Washington, Oregon, Utah, Nevada, and

California.

Some would also include Alaska and Hawaii in this category.

This region is large, and therefore the climate varies greatly.

Climates in this region include semiarid, alpine, mediterranean along California's

coast, and desert in Nevada and southern California.

Physical features of this region are the Mojave Desert and the Rocky Mountains.

The region borders the Pacific Ocean to the West, Canada to the North, and Mexico to the

South.

The population of this region is 67 million people.

The US is a large country, and there are many different characteristics of the regions within

it.

Can you think of some similarities and differences between the Southeast, Northeast, Great Plains,

Southwest, and Pacific Northwest regions of the US?

For more infomation >> Regions of the United States Digital Story - Duration: 4:00.

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'Wreaths Across America,' Wreath Laying Ceremonies All Across the United States of America - Duration: 4:54.

>>> WE MADE THE COMMENT EARLIER

THIS MONTH, I THINK YOU SAID

IT, JIMMY, THAT HONORING OUR

VETERANS SHOULD NOT BE LIMITED

TO ONE DAY BUT IS SOMETHING WE

SHOULD DO ALL THE TIME WHICH IS

WHY IT BRINGS US GREAT JOY TO

BRING YOU THE NEXT STORY.

>> WE ARE TALKING ABOUT

VETERANS WHO MADE THE ULTIMATE

SACRIFICE, THOSE WHO DIED FOR

THE COUNTRY.

NEXT MONTH INCREDIBLE CONVOY

WILL ROLL QUITE LITERALLY INTO

SALISBURY TO PAY HOMAGE TO OUR

FALLEN VETERANS AS PART OF

WREATHS ACROSS AMERICA.

JOINING US THIS AFTERNOON IS

THE PRODUCER AND DIRECTOR OF

TRANSPORTATION, TIM AND DEPUTY

TRUCK DRIVER KEITH CLARK.

>> THANK YOU.

>> THANK YOU.

>> KEITH, RIGHT OFF THE BAT,

THANK YOU VERY MUCH FOR YOUR

SERVICE.

>> THANK YOU.

THANK YOU .

>> WHAT DID YOU DO, KEITH?

>> IN THE AIR FORCE?

>> YES.

FOR THE F-16S, THE AVIONICS

SHOP.

>> REALLY?

>> WOW.

>> WE COULD CHANGE THE WHOLE

INTERVIEW!

[LAUGHTER]

>> IS RIGHT THERE WE COULD!

>> BUT WE WANT TO TALK ABOUT

443-880-9116.

WHAT IS THAT?

>> NO, IN 1992, THE WORCESTER

WREATH COMPANY UP INHERENT IN

MAINE DECIDED TO TAKESOME

LEFTOVER WREATHS THEY HAD AND

DONATE THEM TO ARLINGTON .

IN THE FOLLOWING YEAR THEY DID

IT AGAIN.

AND IT WAS LIKE A SNOWBALL

EFFECT.

IT JUST GOT BIGGER AND BIGGER

AND BIGGER.

>> AND FOR YEARS YOU BEEN PART

OF THE DRIVE TO GET THE RACE TO

ARLINGTON?

>> UH-HUH.

>> ONLY THIS YEAR THEY WILL

MAKE A STOP ON THE WAY HERE IN

SALISBURY?

>> YES.

CONVOY WILL BE IN AROUND 2:30

IN THE AFTERNOON.

WE ARE HOPING EVERYONE WILL

COME OUT FOR THAT.

AND THE CEREMONY BEGINS AT

3:00.

>> SO, KEITH, IS A DRIVER, WHAT

IS YOUR ROLE IN 443-880-9116?

>> WELL, THIS ROLE I WILL

PARTICIPATE IN THE WREATHLAYING

CEREMONY AT THE WAR VETERANS

MEMORIAL AND ON THE 16TH I WILL

DELIVER A LOAD OF WREATHS INTO

ARLINGTON CEMETERY FOR THE

NATIONAL EVENT THERE AT 8:00.

>> GOODNESS.

>> YES.

>> NOW, TIM, THIS IS NOT THE

FIRST TIME YOU GUYS HAVE

PARTICIPATED IN THIS EVENT?

>> NO, IT IS THE 11TH YEAR.

WE'VE ACTUALLY DELIVERED ABOUT

150,000 RATES IN THE LAST 11

YEARS IT CONTINUES TO GROW.

OUR DRIVERS LOVE TO DO IT.

PURDUE GLOVES SPONSOR THEM AS

WELL.

>> WHY?

>> IT IS JUST A WAY TO GET BACK

TO THE COMMUNITY AND OUR

VETERANS.

WE HAVE A LOT OF VETERANS AT

PURDUE AND A LOT OF OUR DRIVERS

ARE VETERANS.

AND IT IS JUST A GREAT WAY TO,

YOU KNOW, PAY HOMAGE TO OUR

FALLEN AND GIVE THEM THE

RESPECT.

I COME FROM A MILITARY

BACKGROUND AND I UNDERSTAND

WHETHER SACRIFICE WAS.

>> RIGHT.

>> AND IT IS JUST THE RIGHT

THING TO DO.

>> AND THIS REALLY MEANS A LOT

TO THE FAMILIES AS WELL,

DOESN'T IT?

>> ABSOLUTELY.

LAST YEAR WAS HER VIRGINITY DO

I WICOMICO COUNTY WAR MEMORIAL

AND THE DRIVER DID ALL OF THE

TALKING, THE FAMILIES WERE

INVITED, A GREAT EVENT.

>> NOW, IS THERE ANYTHING THAT

THE COMMUNITY CAN DO

PARTICIPATE AND CONTRIBUTE AND

HELP?

>> ESPECIALLY AS HE SAID, THE

CONVOY WILL BE THERE AT 2:30

AND WE WOULD LOVE TO HAVE THE

COMMUNITY AND PUBLISHER OF

THEIR BEFORE THE CEREMONY

HAPPENS TO SUPPORT THE EVENT

AND ALSO, THEY CAN VOLUNTEER AS

WELL AT THE CEMETERY TO A RACE

ON THE FALLEN CEMETERIES.

AT ANY ARLINGTON NATIONAL

CEMETERY AROUND THE COUNTRY.

>> IN HERE IS THE INFORMATION.

THURSDAY, DECEMBER 15 AT THE

WICOMICO COUNTY WAR VETERANS

MEMORIAL IT OF COURSE, THE

PUBLIC IS INVITED.

IN THE WICOMICO COUNTY WAR

MEMORIAL FOR THOSE WHO ARE NOT

FAMILIAR, WHAT IS IT?

>> THERE IS 191 HEROES ON THE

WALL THERE FROM HERE ON

DELMARVA.

SO WE HAVE SOME GOLDSTAR

FAMILIES HERE ON DELMARVA.

WE HOPE THAT THEY SHOW UP AT

THE WHOLE COMMUNITY COMES OUT

TO SUPPORT THEM AND REMEMBERS

HER LOVED ONE.

>> AND AS YOU WERE SAYING, IT

STARTS AT THREE.

GET THERE EARLY?

>> YES, THE CONVOY WILL COME

INTO: 30, 2:45.

THEY WILL GET THERE A LITTLE

EARLY.

THE GOLD STAR MOMS WILL BE

THERE TRAVELING IN THE CONVOY,

SO IT WILL BE NICE.

>> AND, WHAT A WONDERFUL

OPPORTUNITY TO ACTUALLY TALK TO

THE FAMILY MEMBERS, THE

GOLDSTAR FAMILIES.

>> ABSOLUTELY.

A FEW YEARS AGO I TRAVELED FROM

THE CONVOY FROM HARRINGTON INTO

ARLINGTON AND I SPENT THE WHOLE

TIME WITH THE GOLD STAR MOMS

AND WHEN YOU HEAR THOSE

FAMILIES YOU KNOW WHAT IT IS

ABOUT.

>> AND WE DO TALK ABOUT

For more infomation >> 'Wreaths Across America,' Wreath Laying Ceremonies All Across the United States of America - Duration: 4:54.

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STTR Regional Technology Transfer Accelerator Hubs for IDeA States - Duration: 1:17:57.

Good afternoon. Hello please mute your phone thank you. Good afternoon I'm Krishan

Aurora, I'm the program director here at the Center for Research Capacity

Building at National Institute of Medical Sciences at National Institutes

of Health, so welcome to this free application Webinar for this

funding announcement or update RFA-GM - 1 8 - 0 0 1 Regional Technology Transfer

Accelerator Hubs for IDeA States. This funding announcement was published last

month on October 20th this is a new initiative that is designed to promote

biomedical entrepreneurship overall the goal of this initiative is to develop

and nurture current and future biomedical enterpreneurs who can

translate the basic discoveries and address the advances to marketplace to

improve and enhance the human life. During this webinar

NIGMS and Center for Scientific Review Staff will explain the goals and

objective the initiative and also other application requirements and also answer

your questions.The regular presenters are listed on this slide the order of

presentation will be, the first part will be presented by the program staff myself

and Dr. Joe Gindhart that will followed by a review, peer review and

considered consideration but after Alan Richon at the Center for Scientific

Review, then we followed by Christie Leake who's a team leader at the Graph Element

Office at NIGMS

Starting with the program part, the intent of this initiative is to score one

shared regional technology transfer accelerator hub in each of the four IDeA

regions that will serve as a network of institution in the in that region these

obstacles served as the regional consortia to provide expertise to

develop the infrastructure and promote and enterpreneurial culture and the

IDeAl institution in that region just to remind you that as they're at work

23 States and Puerto Rico IDeA eligible states. That is 24 into the

entities they have been classified a group into four regions, which has

labeled as Western region, Central region Northeast region and Southeast region.

for example, the Western region includes seven states which are: Montana, Idaho,

Wyoming, Nevada, New Mexico, Alaska and Hawaii. So,

so, each agent has five to five states or seven states depend upon their location.

The purpose of these hubs will be to develop, implement and test a

comprehensive program to promote entrepreneurship technology transfer,

intellectual property, managing business, small business finance and other

business skills that are needed to move basic discoveries and technology out of

the lab and into the marketplace. The goal will be also to generate education

and training tools that will include curricula, text webinar and modules from

the developing, development and testing of the research accelerated models. These

hubs will facilitate networking and team formation between our universities and

small businesses, sharing and transferring information

best practices and guidelines.

The target applicant for these hubs application they will be a small

business company SBC that could be located anywhere in the US where, from IDeA state

are known IDeA state and just that SBC will be required to partner with

academic institution in the IDeAl state to create this regional Network a

successful up should be an inclusive network engaging all the states in that

region the next slide shows this this in scheme wise that this very small

business company that could be located anywhere in the US IDeA are no IDeA

state which will partner with one academic institution instead state one

and that will be partnering with other institutions in that in that in the in

the state in that region to create a city to the network these hubs will have

a mechanism which is a bit as TDR small business technology transfer research

mechanism UT two mechanism this will mechanism either is a is it a

cooperative agreement mechanism and it's a fast-track mechanism that means that

if you involve both the phases of STTR program STTR phase one which will

require up to one year ordered by Phase two which will part two years after this

mechanism is cooperative agreement mechanism that means that the program's

staff from NIH we will have substantial involvement in the program

activities, once they are program funded staff will assist guide coordinate or

participate in the project activities, as needed and as appropriate in terms of

funding these hubs per phase one up to five hundred thousand dollars total cost

per year is allowed and Phase two is up to one point five million dollars total

cost per years.

this slide shows the important dates for this application the one to be

highlighted is the in that which is in that the application due date which are

due on January 5th 2018, and the site also lists the dates for the scientific

merit review when the application will be reviewed

they will pools have enough reviews or one is the initial peer review which is

sometime in March 2018 and as we followed by the Advisory Council review

by at NIGMS will be it will be happening in May 2018 II so the Meritorus

applications they will be funded by September 2018 the letter of intent due

date is listed here is December 5th by that date this state which is one month

prior to the figure should receive dates prospective applicants are encouraged to

submit a letter of intent that includes the information listed on this slide

into the title of the proposed activity name, address and telephone number,,of the

program directors or a principal investigator name or the other key

personnel participating institution and number and title of this funding

opportunity information that is contained in the letter intent allows

staff to estimate the potential review workload and plan that review. The next

part will be presented by Dr. Joe Gindhart. Hi everyone, thanks for joining us. Before

I get started, I just want to make two quick announcements, first, please make

sure that your, your microphone is muted we can always unmute later but we hear

some sounds coming through and then secondly these slides

will be made available but a lot of this information is already found in the

funding announcement so I'll, I'll get started now. The

characteristics of the regional accelerator hubs that is what are we

looking for why did we write this funding announcement we're looking for

teams that have strong leadership we want teams that are collaborative hubs

that strengthen existing resources and fill in gaps in the innovation

environment if you will that these, these hubs should provide training in both

hard and soft skills for faculty and for students at the institutions in the

participating of yeah that are participating in the program the hub

should try to work with existing state and local resources and then finally

there should be a plan for sustainability. This is a three year

program, how are you going to keep this going after, after the the NIH goes away?

Some of the, [okay next slide], so to go into this in a little more depth, we

want to use you, to use the funding that is provided in this one, in this

announcement to leverage with existing NIGMS and NIH funded programs such as

COBRE and INBRE and the IDeA-CTR program and IDeA states, REACH and NCAI centers

which are innovation hubs that are funded in other parts of the NIH CTSAs

and Cancer Centers and then also to, to try to build partnerships with Small

Business Development Centers in the State, Local Government, Economic

Development and Administration Offices and others as appropriate for where you

are. [next slide] So the institutional commitment and regional support, the

problem, that the, please mute your phone Thanks.

The institutional commitment and regional support that we'd like to see

are things like adequate laboratory space, perhaps seed money for pilot

projects at institutions, although this is an optional component we'll get into

this in a little more detail later to change the entrepreneurial environment

at research institutions, by allowing faculty release time for

business development of commercialization activities and

recognition in terms of things like using innovativeation in

entrepreneurial activities as a criterion for tenure and promotion. We

want to see the creation of undergraduate graduate courses in

biomedical technology research, development and entrepreneurship and

then finally see commitment from local or regional sources and that could

either be in kind or just you know letters of support. How are they going to

help you? As far as the leadership team, the big, the big take home from this is,

can the investigator do the work? Do they have a track record of success? And does,

the, does the research plan itself and commercialization plan provide a level

of confidence that if awarded, that the the grant would help us, help us, help you

achieve your goals. [next one] So the what's the, the structure of these

hubs, so the hub feeds a governance team and that consists of the PI and the, the

leadership from the IDeA partner institutions and then there's a series

of committees and just this, this, is described in much more detail in the

funding announcement itself but there's an administrative committee that's

composed of the principal investigator leaders in the small business concerned,

staff an internal advisory committee, that is composed of the the P I and

small business concern staff and, and, and members from other institutions in the

IDeA innovation hub, then of course you need some help from the outside world so

there'd be an external Advisory Committee of local experts, and then

finally a program steering committee, which is a subset of members of all of

these other committees with NIH staff involvement. Okay and then connects like

so some of the hub activities. This is just a sampling of some of the

things that you could do during the course of the award you we would like to

see development of educational and training materials skills development

mentoring and coaching internships consulting and advising of

investigators that have IDeAs that, that could be commercialized to help people

learn how to prepare an SBIR/STTR applications so SBIR grants have a phase

one of award, and a phase two award, these would be phase zero activities. If you

want to think about it that way once again changing the culture a little

bit to create an entrepreneurial culture in which these sorts of activities are

not, not treated either neutrally or negatively but positively and then once

again to bolster the tech transfer and commercialization offices in the region

and then you know, we'd like to see your ideas to it, so what can you bring to the

table? what are your neat ideas? we'd like to know more about that and then [let's

see next slide] [cough], so excuse me, so the some of the what are the milestones of

success for this, for this funding announcement, we would like to see you

know, you could measure things like the numbers of, the number of faculty who are

participating in this the development of curriculum and skills development

materials a number of patents number of licensing agreements increase in tech

transfer from from time zero to two at some point during the course of the

awards, you could, we could look at the number of startups focused on

biotechnology that were launched from this award. In some of these I should

note that some of these milestones couldn't be measured, you know in year

one of the award or year two or these might be things that we could measure

five years out, let's see and then you know so the long long term goal is to

increase biotech related jobs and economic activity and IDeA states.

Alright okay, so what's the application going to look like, so Alan will speak

about this in a little bit, I think, about the specific games page of course and then

there's a research strategy which is 12 pages long and that has what you would

expect, there's sections on leadership and governance collaborations and

partnerships, skills development, writ large plans for sustainability ,program

evaluation and then once again there's more information about this in, in the

RFA itself about pilot projects and then the commercialization plan, we didn't

leave the information out of this slide the commercialization plan is the same,

that you would find in a regular STTR application so if you have some

familiarity with that, you can, you can look into it and then let's see. So

finally, a part one of it one of the components of institutional commitment

could be these pilot projects which are as we'd like to emphasize again an

optional element of the hub, you can't use federal funding to support this

activity, so we are sympathetic to the notion that, some consortium may

have more funds to do pilot projects than others but that will not be a score

driving, a score driving issue, the pilot projects are intended to demonstrate the

feasibility and group of concept studies for innovative products biomarkers or

diagnostics the pilot projects would not be proposed in the application itself so

if you were intending to do pilot projects during the course of the

project you would talk in the application about how you would solicit

applications or pilot projects and how a pilot projects would be selected but not

like what the specific projects are themselves and okay so I think with that

I'll turn it back to Krishan. Yes, because as Joe mentioned, that you know

the application has a number of components and those are, these hubs will

be partnering and collaborating with number of institutions in the IDeA

States and also the number of other entities who are local or state resources so

it will be important to include letter of support that will highlight that, there

should highlight, how these hubs will leverage existing resources and also

avoid duplicating the efforts in there and there, won't have activities and some

other resources may be available at a state level, local level, that could be

used by the hub, so there's no need to duplicate those same resources or

activities, so in terms of the natural support, could be from the letters from

the atomic partners or consultants, contactors a collaborator as appropriate

which are needed and for the hub to meet some goals and objective of the proposed

project also the level of support from the senior leadership and the active

partner institution will be also critical and they should those letters

will outline the resources and the facilities that will be committed by the

institution to support and sustain the detail throughout the period of

funding and beyond and also this letter of support would be

also included, from the program that will be participating leveraging the

resources from the IDeAs portal activity like COBRA, INBRE, IDeAs CTR other

Centers, REACH fundraiser reach our NCI Cancer Centers, so those other should be

included with the application also that is indicating the support our resources

are available from the state, our local government agencies, other groups such as

business development organization, that could be partnering in the of activities

they care, they should, we also include,

so as I mentioned earlier, that there is a faster application, we have both phase

1 and phase 2 and to transition from phase 1 to phase 2 that will be

administrative review by the NIGMS program step and this is specific

milestone and criteria which the hub has to meet for entering from phase 1 to

phase, phase 2. So these are listed on this slide but they are taken straight

from the funding opportunity announcement which include, that there

should be functional communities as you measure that there are number of

communities fighting each other propose of the additional community internal

Advisory Committee programs at the External Advisory

Committee, they should have been all established and number the sub structure

governance and leadership plan secondly the other contractual arrangements

between the Business partners in the IDeA region are the Memorandum of

Understanding should have been established in the phase, in the phase 1

phase, for face-to-face in one stage, also during the phase one state, there is a need for

assessment on the infrastructure for further academic partners and how they

are going to be address the implementation, implementation plan.

This should also formulate the goal is to this research repair capacity and

infrastructure to promote biomedical enterpreneurship

at this institution in that region also xantham know that because it is

educational program to mentor and consult a consulting the faculty was

innovative and who want to translate the basic discoveries to marketplace so in

terms of the what kind of skills that they need to learn and whatever their

learning needs are there what is available in the local ecosystem the

resources part is relevant content and also what are the plans for developing

additional content for education and workshops webinar etcetera so that

criteria should also be met in the face from fear of us are moving from

pays to also doing a phase one the hub should develop a prototype in terms of

training and education resources for faculty most of fellows graduate

students and undergraduate students also to a establish a system for delivering

the webinar webinar organizers of webinar and visiting the academic

institution for an outrage so that material should be also met from were

transitioning from phase 1 to phase 2

the goal is to support food retail hubs which are shown here again on the

receivers map highlighting the four regions for example this is shown on the

western region the hub which will be partnering with all these seven states

in that region similarly for the next standard leader the hub could be located

anywhere in the state and then they will be partnering with the five states in

the sense of vision the next one is luggage is the southeast region again

thus that will be partly with the southeast States

and the fourth one is invisible Northeast region and that we'll be

partnering with five states in the North disappear and it's also expected that

these food hubs will be interacting among the temple for shading and

leveraging the resources that will be created through these other activities

so as you'd want to know dr. Allen rochonc

the scientific review officer say thank you good afternoon I put this funny I

have been running SBIR reviews for about nine years at NIH and so this is kind of

blend butter for us we look forward to work one what happens when your

application comes you can spend time putting it together you upload it the

the USAJOBS or grants.gov website and it will go to the division of receipt for

referral from there will be sent to me because I am assigned to the content

review officer for this particular RFA and once it gets into my hands then I'll

be putting together a panel I think you probably like to know what are the

various parts next um I will act as the federal official who's responsible

process that means I have legal responsibility for making sure that all

rules regulations best practices and so on are followed I will also perform

administrative review of the applications to make sure they're

complete and make sure that they are accurate comply with the requirements I

will then find reviewers once we get them together and I'll talk about that a

bit I will manage how to study sections run and then take those results prepare

summary statements and send them both to you and to program excellent please I'll

be working closely with the study section chair who is a senior level

scientist probably somebody that has their foot in two worlds this will be

someone that who's dealt with technology transfer in their past lives

and in small companies but in large companies worked in academics and so on

that person is going to be responsible for actually conducting the meeting

guiding the discussion making sure that all points are heard making sure that

all opinions are heard and they're just managing the overall process in addition

time the next one please we will have any essay or extra mural or assistance

this is the person that will be making sure that program officials can hear the

meeting that the telephones are running well managers travel that we have that

particular aspect of it and then shares the administrative responsibilities so

and then finally the panel what we look for is expertise that matches the

content of the application so in this case we are going to need scientists

that have expertise in a wide variety of areas people that are mature ie

they've been in the career for a while they've seen a lot of things in the

course of their careers they have a breadth of perspective they will be

impartial and we try as best possible to get academics and Industry experts we

want at least 25 to 50 percent the from small businesses or from tech transfer

we also make sure that we have women and minority scientists there geographically

distributed and especially for this one we will be finding people that have

commercialization and Technology experience both in academic centers as

well as the industrial institutions I don't know if you're aware that large

Pharma has entire divisions entire groups that are responsible for bringing

technology into the organization from small businesses from academic centers

and so on those are the kinds of people were looking for because they'll be able

to have an informed opinion on what makes a successful Center next slide

please each application that we get will get

three or more reviewers and the reviewers will have access to the

applications five to six weeks in advance during that five or six weeks

they constantly get bombarded by me reminding them that they've got

responsibilities to make sure that these things are done we try and have the

applications and their comments on it uploaded to the system week before the

actual meeting so that everyone has a chance to read the comments and get an

informed opinion on each application and the reviewers will be responsible for

providing an overall impact score and will tell you about what that means in

just a bit as well as criterion scores on the various review criteria sections

they will provide a written critique so each person that submits an application

gets a view of their application from three different independent reviewers

next slide please the criteria that we're talking about

are pretty standard in all small business applications and it's basically

how significant is the work who's the team that's going to carry it out what

level of innovations do they bring to the table and how they're trying to

approach the problem how are they actually approaching the problem and do

they have the environment to do it who basically what we're saying is tell us

if what your IDeAs is tell us why you think it's a good IDeA tell us why you

think you're the person that can carry this off tell us how you're going to do

it using the best technology that's out there and put it together in innovative

ways tell us what you're going to do is to encounter problems what things you're

going to try and work around how well you're going to plan it and tell us how

the environment that you're putting together is going to help to accomplish

the objective and that all boils down to the overall impact if you read the RFA

it's to assess the likelihood that Club is going to function as a way of

bringing technology out of the region and then do it in such a way that

innovations get developed and distributed to the u.s. through your

particular institution each of those five criteria gets a score from 1 to 9

one being best 9 being worst and the overall impact is also 1 to 9 when all

of these scores come in reviewer scores the average and then

many applications will be rank ordered and that will be the discussion work so

we'll start with the best scoring application and work our way through to

the one that doesn't score as well

depending on how many we get we will cut off at a 50% level I doubt that we're

going to hit that level with this particular RFA in our standard small

business application panels we have somewhere between 60 and 100 application

and it gets really tough to try and talk about every one of them so that's how we

make the cutoff and the next one please okay in addition to those five areas

with this RFA there are other areas that will be considered as score driving and

they will contribute to a score for either significance or approach but they

won't be scored individually and that is going to be how well is the impact of

the hub described and the organization of the hub described what skills and

educational programs do you bring into the system how are you going to develop

those how are you developing the tech the capability to bring technology

transfer to the region how well do you manage projects how well do you meant or

what consulting arrangements are using to make how are you going to advise

people what kinds of programs are you going to put in place to make sure that

these things are done that is going to form the core of a lot of the

discussions frankly next please in addition um this is a fast track and

that means that it has to have two distinct phases in Phase one you're

basically setting the stage for the work that you're going to do in stage two so

we need to know front of your viewers need to know from you what are you doing

in phase one and how are you going to measure whether you're successful or not

now those milestones should be clear they should be appropriate to what

you're trying to do and they should be quantifiable and measurable so you know

nothing really washy like wishy-washy like well we're going to try and do a

seminar to tell us how many what kinds of things

going to approach the more specific would be the better the reviewers are

gonna respond to it and so once you have met those goals you can put together a

report that's sensitive program they'll evaluate how well you've done and then

you go into phase 2 that's where the actual guts of the work gets done so we

need to see the transition and keep in mind when these things for fast track's

come in to small business study sections reviewers are really tough when they

don't see a distinct phase 1 and phase 2 so that's just a warning ahead of time

next please commercialization you have 12 pages to

describe what you're doing you've got 12 pages to describe how you're going to

roll it out as a self-sustaining product what we like to see in the review panels

are who are the people that are going to do this and do they have patience to

manage it do they have a commercialization strategy so they've

got some way to measure how they're going to get it out there they have some

way to make sure that it becomes self-sustaining they have follow-on

plans that say this is how we're going to fund it from years three f2n very

important are letters of support so from small businesses from academic centers

from investors from wherever you can find any strong letters of support that

will show that your plan is meeting with the needs of the community at large will

help to enhance your commercialization strategy next one please

there are I doubt that we're going to be seeing these things but if you are

planning any human subject studies and that could be things like surveys it

could be things like taking a seminar and getting feedback from the

participants those types of things are human subjects of studies and so be sure

that you look at what the protections required are those are in all the NIH

documents when you do that you need to include representative sampling of the

people in your region so women minorities children

that's anyone under the age of 18 now um vertebrate animals I don't think

we're going to be doing any squirrel case studies here so I don't think

that's a group that's appropriate but basically if there are four things that

you need to cover I don't think we'll they'll do any

biohazards but those are kind of the standard pieces on every type of

application that comes in to small business if it's not applicable fine but

if you're planning on doing it please check with the NIH documentation see

what you can simply next there are other things that we asked reviewers to look

at they do not affect scores they're non scoring issues any time that you're

doing a large-scale application if you're going to be generating data if

you're going to be generating new organisms new bottle organisms if you're

going to collect only data if you're going to involve foreign organizations

we need to understand what you're doing with those so be sure that you cover

those select agents there's a list up in 1:08 website I doubt you're going to be

using any Ebola or things like that that's what those cover and key

biological and chemical resources is if you are going to start working in lab

and you're planning on doing cell cultures for example make sure you tell

us that you have saved themselves and that they are what you think they are

and then budget is the final piece we asked reviewers simply to tell us is the

budget reasonable for the work that you propose they're not going to get into

the minutia budget that's programs issue they've we just advise program that yes

the budget batch is kind of the scope of the work that is being proposed okay

next as I said it's a 1 through 9 in general we look at anything scores a 1 2

3 as having a high impact 4 to 6 as a medium impact and 7 to 9 is a low it

back and you can see that there just appreciate next please after review me

one of the things that I think is the least understood by applicants is what

happens and unless you've gone through a study section it's kind of a black box

the chair will pull three primary reviewers and ask them to

state their preliminary overall impact scores now those are going to be the

ones that they put down on their application and then maybe slightly

modified by what they've read that their colleagues have said as well reviewer 1

will spend the most time they will introduce the application to the panel

say what's good and bad about it say where the strengths lie say what the

overall objective is and since most of these are similar types of activities

those objectives are pretty much going to be the same I had I had to guess

reviewers two and three will then offer any points that weren't covered by

reviewer 1 and at the end of that the discussion is opens the entire map given

that there will probably be complementary expertise I have a feeling

we're going to have very active discussions during this the whole panel

is welcome to ask questions make comments raise issues that conversation

will go on until all the topics are exhausted and after it's finished the

chair will ask the primary reviewers to take to state easily their final overall

impact scores and those are the scores that will be reported to program and to

you once those scores are given everyone on the panel is asked to score similarly

so it's a little federal range so it's a 1/3 that will be the range the panel

then will score within that range unless they hear something that they think they

substantively disagree and it could be based on their research in the area it

could be any number of things that reviewers are free to vote outside that

range we just ask that whatever the reason they're doing it has been

discussed and if it hasn't then we reopen the discussion and we bring that

point forward every piece of information needs to be considered for every

application to arrive at the final score so if we have 20 people on the panel

there would be 20 scores unless a month in conflict and they'll be out of the

room during this discussion so those those scores will then added together

averaged and multiplied by 10 and that will be your final overall impact score

okay next one please once the meeting is finished it's my responsibility to take

all of the said during those discussion and boil it down to a paragraph or two

hits the highlights that will be the resume of the discussion it will be

attached to the three critiques I then go through and clean up all the applique

all the summary statements make sure there's no bad grammar make sure that

there's no inaccuracy if there's things missing I will contact reviewers that

issue those critiques and say hey I need more information here that usually takes

about two to four weeks after the meeting the final overall impact score

and then all of those will be sent to program and to you

and next okay thank you other next presenter is a Chris Gilly hi everybody

I'll be going over some budget considerations for car registrations and

eligibility for this fo way so there are several required registrations for the

main applicant which is the small business concern please make sure to do

these in advance several of you take several weeks to set up you want to make

sure you have those in place well before the due date of January 5th so you need

to have your Duns number your system for award management your SBA company

registry an era Commons account grants.gov access as well as ensure that

all of your P is your PDP is have the era Commons account so this there is

actually quite a bit of eligibility that's around grants for SBIR STTR

awards all this information is well outlined in the FAA as well as several

websites so just please pay attention to that eligibility criteria to make sure

you're eligible to apply for this funding opportunity in addition there

are for the STTR portion of this award the PD or PID

may be employed with a small business or a single partnering nonprofit research

institution as long as she or he has a formal appointment with or a commitment

to the applicant small business concern and for this FY multiple PD API

Arrangements is allowed that's less so because this is an STTR the small

business concern will partner with one main research institution as well as

several others so for of a phase 1 and the phase 2 at least 40% of the research

or analytic effort must be performed by the small business concern and at least

30 percent of the research or in a little effort

must be performed by the single partner in research institution the remaining

30% may be attributed to either the SPC primary research institution or

additional third-party organizations I mentioned earlier the contractual

arrangements or memory and understanding must be established between the SPC and

a partner in institutions as part of the phase 1 scope Shawn briefly mentioned

the budget budgets of up to $500,000 our total costs per year for phase 1 awards

may be requested and then for the phase 2 budget up to 1.5 million dollar total

cost per year may be requested please pay attention that this is a total cost

cap on these awards not direct cost and for a brief mention of the FN Averys for

the small business concerns please one applicant you do not have a negotiated

F&A rates should have both an estimated rate not to exceed 40% of the total

direct cost and a reasonable fee not to exceed 7 percent of the total cost which

includes the direct and indirect for each phase of the project is available

to the small business in turn this is intended to be a regional profit factor

available for for-profit organizations

so for budget considerations specific to this fo a each PDP I must minimum of 10

percent effort to the project fund should be requested for the hub PDS and

pis and other hub staff as appropriate to attend the annual in person program

steering committee meeting in Bethesda Maryland fund should be requested for

the operations of the external Advisory Committee and there's a long list of

other allowable costs as described in the FOI that should get clear to the

applicant this slide I often put up for potential grantees of potential

applicants as things to keep in mind when putting together an application

these specific costs are things that often jump out from my office aggressive

management office the general thought is to make sure that all of your costs are

well described and well justified and make sure that they are appropriate to

the proposal that you're submitting additionally if you have more questions

about how a cost the NIH grants policy statement is a great tool to use there's

a section for selected items of cost as well as there's a section of the uniform

guidance selected items the cost that will be helpful as well

Thank You Christy so finally to wrap up the just to some reminders the final

reminders for the program as you those prospective applicants start either

preparing this application I'd like to emphasize to read and follow all that

destruction in the funding opportunity announcement and make sure that all the

new criteria are addressed and also some of the features that I mentioned for the

up that is small business concern that could be located anywhere in the US

women IDeA state or in an non IDeA state SBC must partner with academic

institution in IDeA states to create an inclusive regional Technology Transfer

accelerator hub and you can include consultants experts advisors coach

mentors from IDeA are known IDeAs state as you deem appropriate to Musa polls

and objective of this funding announcement an application a so must

include with a fast-track mechanism must explore milestone that will be achieved

for transitioning from phase 1 to phase 2 as I just like to remind you that the

potential members as you know that a external Advisory Committee is a

required Committee for this program or these hubs the potential members of this

ESC should not be named and should not be contacted prior to the review of an

application but you may discuss in the application what type of expert is the

individual will have that will be looking part that you can discuss the

expertise in the application or not name or contact the EAC lambdas and all vse

members so finally a goal of this initiative is to create these regions in

each of the four IDeA regions that will be interacting among themselves within

the institution as a state and it will be creating a education programs to

develop the skills mentoring coaching consulting to those at innovative

faculty at this institution and to create this enhance this

enterpreneur ecosystem that will provide education connections and support to

develop in terms of commercialization capacity that can facilitate the

translation of discoveries and advances from lab to market place to meet the

societal needs so the data will stop here now and we focus our questions

hello I have a couple questions from you nummy yes

oh okay great thank you thank you for the information stay very very helpful

very useful the 12-page research strategy and the 12 page commercial plan

is that the requirement for the phase 1 and the phase 2 combined or is that are

quite requirement for each section phase 1 and phase 2 individually

you will have 12 pages to describe your research for both phase one and Phase

two and then twelve pages as commercialization niche

commercialization plan it's an entire document okay

great thank you and it sounds like the expectation is to develop a prototype of

courses in during the phase one portion of the research plan and six six months

generally for Phase one as we know that's a tall order to develop a

prototype of a curriculum in six months am i understanding that requirement

correctly

this one is part two of one yet so you have for 12 months

Oh one year okay thank you that makes more sense to me thank you very much

yeah I agree six months would be a short timeline and on finding the University

hub partner or the the research institution one on the diagram if

universities are competing for the opportunity to be the hub in a region

it's good a challenge I think to find one University willing to be the hub and

then the rest serving as supportive offshoots of that hub had that challenge

been discussed in the with the team that's developed the topic or the RFA so

so I think you know if you think about it in the context that the small

business concerned is 40% 40% of the budget the first institution the main

institution would have a minimum of 30 percent of the budget and that would be

the core of activity of activities and then they would reach out those two

groups working together would reach out to institutions and the other IDeA

states so it's of course that the arrow goes both ways that there will be some

contribution from the from the the satellite institutions if you will to

the to the the SPC and if the main institution but we think that there's

incentives for institutions to want to serve as the main being part of the hub

I don't know Prashanti I thought also actors actors I don't know that this is

for the IDeA program that we have been funding last 15 years be encouraged I

was networking a collaboration among this situation within the region and

among the regions so I think they would like to kind of know participate you

know in this initiative and the partners within the

hub within the Hobbit

you

my question

does that answer your question we have another question can we ask it sure

could you say what the definition of an academic institution is for the purposes

of this specifically does it need to be a degree granting institution or one

which has meets other requirements such as advising students and adding a large

flow of tech transfer the traditional definition has been an academic

institution a nonprofit organization or there's one other piece there that

escapes me at the moment but it's not just a degree granting institution

now whether program wanted C's to be specifically academic I don't believe I

saw that in the RFA no if you're--if institutions have eligible to apply for

an STTR grant or to participate in stitute and an S qtr grant they should

be able to apply to this as well I'm thinking specifically of a National

Laboratory well that's a good one we'll have to look for that thank you

you should reach out to us in Tibet in a couple of days or even email us tonight

and Dhaval will follow up a bullet of you thank you okay thanks

I'm curious as to what you're thinking in terms of the small business concern

are you thinking of a small company are you thinking of a business incubator or

an accelerator or what is your sort of thinking on those lines

well it would have to be Krishan and I talked about this a couple days ago it

would have it would have to be a for-profit organization okay that's our

body's harming can you I'm sorry repeat the question answer on that who has to

be a for-profit institution so the club sorry so the question is what type of

organization could be the business concern does it would it be a company or

could it be you know sort of a business tech innovation hub or a some business

development organization and the the criterion for the small business grant

is that would it would have to be a for-profit organization okay thank you

okay and I think rashon now is going to read a couple of the questions that was

that we've gotten online

let me read it crucial yeah okay so the first question that we got by by WebEx

is do the institutions representing each state need to be the homes of existing

Embree or Cobre programs I know it would have to be the home part I interview

public program but they could be partnering it over and the some of the

resources that have been funded to an IDeA program they can be leveraged at

this from the institutions that are funded to the IDeA envy program and then

there's a question is there an expectation that an academic institution

collaborating with an SPC on this hub grant will have an existing track record

of success with NIH grants eg rl1 and other NIH grants mentioned in the

presentation I think that you know there there is the if you look at the criteria

for investigator of the review criteria that could play into it a little bit but

it certainly isn't the whole story that we're looking for organizations that

have the skills and the expertise to to to do this project regardless of their

their prior track record you should know that year year after year about a third

of the small business grants that the NIH grants are to organizations that

have never had an NIH grant before the next question that medicine is a ten

more than one institution by institution duties which is a lot more MPI's

obviously multiple pis so the answer is that no it would have to be one main

small business concern that would be the prime institution the whole point of

that the there'd be one small business that then partners with one research

institution so there should just be one main FCC

multiple PI's are allowed it's up to you how you set up your multiple PI

management plan the next question is a 10-month mode and monopolization odd

individuals participating more than one proposal submission within the region

are worth a salute to the disqualification of the applications if

there are two I mean to small business companies they are trying to create a

hub in the same region and they could barter with that the same institution

but with a different company so we can have received two applications that way

from two different SBC partnering with the same institution yeah and we got

into the you know it gets into the question of what counts as overlap and

in NIH grant and you know Ellen might be able to speak some of this but can you

imagine that if one small business concern wrote two grants both for

innovation hubs in the southeast I think maybe you would consider that overlap

yes but what if they wrote a innovation hub for the north the same small

business concern wrote an application for an innovation hub in the Northeast

versus the central rienne the central region maybe that wouldn't be overlap I

don't know what do you think cor will consider that overlap with a so same

type of activity ootek in those in different areas okay

so the same remedy that's good I guess from the same one SPC connector to

partner B the Budokan region and some into different application right so

that's multiple applications from an IDeA region

Karen's a human institution participate whether that two different small

business concerns in the two different necklaces so do you mean say let's just

not the let's just say that the University of Kentucky has two

applications one with two different companies the company two

different companies put the same institution and the company submitting

the application let get those to commend Institute you be on both okay that's a

tough I don't know the answer I was like yeah yeah I digged entity other people's

I got a fun one yeah yeah yeah so so we think that so the question was I don't

know if you heard it um so could an individual institution partner or

sending multiple applications and I don't think that the funding

announcement precludes that but once again it gets into some of the issues of

overlap if the if the main partner institution is proposing the same

activities in two different with two different companies that could be turned

into an overlap issue perhaps yeah I think it's a question of the small

business concern is the one that's going to be the main focus and then the tech

transfer out of the academic centers that one's a little more muddy if you

will so the small business concern proposing the same thing in different

regions that's okay but the Associated academic centers with the commercial

organization I don't know I'd have to I'm gonna have to check on that okay so

yeah that's another thing at home yeah

I just have another question just to kind of triple-check the small business

concern I think what I heard is that it has to be a for-profit entity and

because I'm thinking that's you know a tax status

you know for-profit or not-for-profit so is that really the hard definition of it

there's a there's a long list of eligibility information in the fo a the

number one point for that is that is organized for-profit with a place of

business located in the United States which primarily operates within the

United States so yes it has to be a for-profit okay thank you

the next question is is the Administrative Code to be composed of

both SBC offices and partnering institutions representatives or that

could also I think that that actually would is that the internal advisory

committee or is that the the administrative penderson at it yes it so

that so the question was again is the administrative core to be composed of

both SBC officers and partnering institution representatives yes next

question is may current NIH commercialization support contractor

participate or would this be considered a conflict of interest that's probably a

conflict of interest for anything I'll check that to make sure because if you

can check on this one and get back to you

that's good let's go down some more yeah I think I see okay

and then there's what is the scope of biomedical disciplines that are

considered to be important for this scheme is there a focus on a particular

area but the short answer is the the particular area of interest would be

research sets within the NIH mission

that's pretty broad yes by recording the question is release recording be

available later yes this will be available two days after the webinar

so we will post it on the IDeA website

can a non-profit known research institutions be Co PRA I am not actually

sure of that question a COPI I I don't know that a non-profit non research

institution would be part of the hub it doesn't seem like you know that the

small business concern the research institution in the IDeAs state and then

other research institutions in that IDeA state are what we're looking for is part

of the network a non-profit non research institution doesn't seem like it would

fit in this although a little in the context of a thousand anciano in the

context of a co-investigator someone they could have a subcontract with well

I think you asked the question and the reviewers would be looking for how does

this organization contribute to spraying technology to the US and if there's a

way that they do that then potentially it would work but you know I can't

understand how a non-profit non research institution is going to see the same

spread technology and then there's a comment it may give

the wrong impression if the same company competes and wins more than one Center I

think we decided that because of overlap issues that that wouldn't happen that

that a company could only give one of these right right

well the next question is I was very confused if one company can sum it to

two different regions assuming that the people within that company are different

so that there is no overlap it's still the same confidence it's the same

company and conceptually it's very similar applications come from companies

not individuals

when you look at curricula is there any bias to certain existing materials like

ICOR for the SBC creation of IP it will be important for commercialization.

So, yes you're right, ICOR is one example of a way to do this there are other

examples of ways to do this, so you know you my advise would be to use your best

judgement. There's no bias one direction at the end. The next question, is must a

applicant have a participating institution in each state or is there

flexibility on this? It should be an inclusive regional network so all the

states have been involved in that Network so at least one institution

should be part of the hub from each state. Is there a significant benefit of

being able to have cash matching commitment from a state government or

from commercial partners participating in the IDeA hub? That's a good question, it

it's difficult for us to get into the minds of what the reviewers are thinking

but, you should look at the review criteria that there is no, there is no

cost-sharing requirement but there are a number of criteria that go

into determining what the strength of the strength of the application are and

so that would be my advice is to go back and look at the review criteria. I was

surprised to hear that lab space was an indication of commitment, there are no

wet lab activities relevant to this FOA please clarify. I think that, okay so

that your your right, to that does sound odd, out of context but we're talking

about partnering, there are institutions that are more research intensive

than others in IDeA States and one of the action that

there were there were situations where people needed, needed space to do

activities that they couldn't do at their home institution, could they get,

could they do those experiments on another campus, for example?

Are there any space for any activities they proposed? Yeah, you're not

trying to limit what an applicant can suggest, um if they have an IDeA that

involves generating intellectual property in a lab, then that option

should be there. I don't think it's a requirement, I don't think there are any

hard requirements on any of these, it's just, it's an option.

Is it better to include partner institutions with tech transfer

capabilities or should we try to include institutions that need more assistance

in this area? I would look at it as it's a blend of the strengths. If your

institution is strong and tech transfer and then you have other institutions

that have IDeAs the way to get them out and that would be one scenario. Another

would be, you've got great IDeAs with no tech transfer, so what do you do with it? So

it's a blend. I agree, I agree that you know, what is the

way that you can, you know, it's a balance what is your, what are your current

activities that would be part of your strengths but then what is the impact of

the activities to how do you, what's, what's the slope of the curve

from, from now to you know, three or four years from now of improvement of the

infrastructure in your, in your region? So regarding the Commercialization plan,

is that focused on sustainability of the effort, commercialization of products

from the beneficiaries of the training or mentoring or commercialization /

sales of the training materials themselves? It's all of these. It includes of them, all of these. [laughter]

all of these yes, yes, yes, yes.

Is there preference between a participating, one more question, it is not really a question,

it's more of a statement. Is there a preference between a participating

public or a private university? No, Preference. What help is NIH giving

referring to your cooperative point made early in this presentation, can we expect

NIH to dictate certain methods or processes? This part comes after the

award is made, you know. In terms of cooperative mechanism you know, once

the awards is made and the hub's are funded then NIH will have substantial input

in terms of the planning and overseeing the activity of the hub. Is participation and support by

multiple institutions from each state encouraged? Yes. What if one state only

has a few institutions that have come together and do not want to partner

because they are proposing their own hub, how should we get support from that

state, if none of the institutions want to partner, but we have support from all

of the other states?

It seems a tricky part. That's the first year, we need to deal

with it this happen in IDeA state where it can't compete. They need to come together. Yeah, part of

the goal of this is getting people to work together and I think that sort of a

bad sign, if at the application stage these things are coming to the

surface. NIH has done several hubs from genomics to data sharing to

chemistry and screening and I think all of those dealt with the same types of

issues and they get resolved. The next question. Any incentives to include MSI?

Do you mean Minority Serving Institutions, then yes, of course. So I

think that's a similar question for any incentives for any underrepresented

groups? Oh I don't know what you mean by

incentive, but that, key part of the NIH and NIGMS mission is to

broaden the diversity of the biomedical workforce. So this, is this FOA intended

to one, create a single regional tech transfer office to facilitate the

regional transfer of technology through the office of research to accommodate

for what has been identified by NIH by NIH IDeA 2014 workshop on SBIR/STTR

existing week local tech transfer offices or two to support a network of

local tech transfer offices and their affiliated existing accelerators to work

together collaboratively to provide resources with a small business concern

as lead? Those are two different models for doing it, I think you just

have to weigh your options based on the conditions on the ground, where you are.

In case NIH has funded similar programs before, could you please give examples of

the kinds of industry partners that would be the best fit for NIH IDeA hub?

Probably the ones that match the technology that you're working on and it

doesn't make sense if your particular areas are strong in cancer research, for

example, that you would be interested in doing environmental impacts sets. You

know it just depends on what what you see is the strength of your area and

what you have in terms of industrial partners that are around you? Yeah and we

really can't dictate that. No, no one thing you could do is go into

NIH reporter and search for small business grants that are doing the sorts

of things that you're interested in doing. That, that's one way that you

can identify organizations or companies I should say, that have been successful

in getting grants in this sort of stuff and you could all always reach out to

them. What would be desired roles for local tech transfer offices if

any in this regional technology transfer accelerator hub for IDeA state? Yeah, I

mean if there are local, if there are local tech transfer organizations that

have expertise that would benefit this, this project, then they have a role to

play and they can partner with the hub and share IDeAs and resources and

provider expertise as the case may be.

They can contribute to regional seminars, they can contribute to

business development activities, there are a whole range of things.

There is Stretten application and if you can include those

as a partners, you know, the local the technology transfer offices

the proposal.

Are there are there any other questions?

I'm gonna, not question, if it, at this time. I mean at this time, if you can send us your questions

by email we'll try to address those questions and

we'll make available the recording of this webinar and the slides on the IDeA

website within two days, after two days.

Was going to ask the FOA, I see the notice of intent to publish the FOA on the

internet, I found that, but the actual FOA is that out? Yes, it was published

October 20th, so the number is RFA - GM - 1 8 - 0 0 1, RFA - GM - 1 8 - 0 01.

Beautiful. You could also, has a link you know, like go right there yeah, just Google it.

That's what I do, you will see it right away. Oh yeah, awesome.

Thank you all for joining the webinar and all the best. Thank you.

Thank you very much.

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